Hugh has single-handedly saved "polypragmonic". But there's still work to be done. From The Times:

It may appear agrestic to ask, but The Times is calling on its readers to come to the rescue of words that risk fading into caliginosity.

Dictionary compilers at Collins have decided that the word list for the forthcoming edition of its largest volume is embrangled with words so obscure that they are linguistic recrement. Such words, they say, must be exuviated abstergently to make room for modern additions that will act as a roborant for the book.

Readers who vilipend the compilers’ decision and vaticinate that society will be poorer without little-used words have been offered a chance to save them from the endangered list Collins, which is owned by News Corporation, parent company of The Times, has agreed that words will be granted a reprieve if evidence of their popularity emerges before February, when the word list is finalised.

Arguably we should get rid of the word "finalised", as it is vilipendiary. (I don't know if that's ever been a word but it is now.)

Times readers can help to lift the malison on their favourite word by voting for it at the Comment Central weblog on Times Online, which will use its influence to persuade the public that the winning word is compossible with everyday speech.

Some words on the 24-strong list will also have a lucky periapt in the form of a celebrity champion, who will attempt to overcome their word’s caducity by using it in speeches, articles and on television.

Stephen Fry has chosen fubsy, which describes some of the contestants on QI, the quiz show that he presents. He may be able to persuade scriptwriters of Kingdom, the drama in which he plays the eponymous solicitor, to include the word in its third series.

[...]

Vince Cable, the griseous-haired Liberal Democrat Treasury spokesman, hopes to revive niddering by using it in his speeches. “It has a sort of withering contempt about it that is useful for political invective,” he said.

[...]

Words without champions will rely on Times readers, who will have to decide whether words such as mansuetude are sufficiently nitid to save, or too olid to contemplate.

Some of the words heading for extinction:

Abstergent Cleansing or scouring
Agrestic Rural; rustic; unpolished; uncouth
Apodeictic Unquestionably true by virtue of demonstration
Caducity Perishableness; senility
Caliginosity Dimness; darkness
Compossible Possible in coexistence with something else
Embrangle To confuse or entangle
Exuviate To shed (a skin or similar outer covering)
Fatidical Prophetic
Fubsy Short and stout; squat
Griseous Streaked or mixed with grey; somewhat grey
Malison A curse
Mansuetude Gentleness or mildness
Muliebrity The condition of being a woman
Niddering Cowardly
Nitid Bright; glistening
Olid Foul-smelling
Oppugnant Combative, antagonistic or contrary
Periapt A charm or amulet
Recrement Waste matter; refuse; dross
Roborant Tending to fortify or increase strength
Skirr A whirring or grating sound, as of the wings of birds in flight
Vaticinate To foretell; prophesy
Vilipend To treat or regard with contempt